Comedo, the primary sign of acne consisting of a dilated (widened) hair follicle filled with keratin squamae (skin debris), bacteria, and sebum (oil). Comedones may be closed or open. A closed comedo has an obstructed opening to the skin and may rupture to cause a low-grade skin inflammatory reaction in the area. The common name for a closed comedo is a whitehead.An open comedo has a wide opening to the skin and is capped with a blackened mass of skin debris. It is commonly known as a blackhead.
Acne occurs when sebaceous glands of the skin begin to secrete oil during puberty. These glands are stimulated by male hormones that are produced in the adrenal glands of both boys and girls. The oil lubricates and protects the skin. Under certain circumstances, cells that are close to the openings of the sebaceous glands block the openings. This causes a buildup of oil underneath the skin. Bacteria, which live in everyone's skin but generally mind their own business, feast on this oil, multiply, and cause the surrounding tissues to become inflamed.
If the inflammation is right near the surface, a pustule is formed; if it is deeper, a papule (pimple); deeper still and it becomes a cyst. If the oil breaks though to the surface, the result is a whitehead. If the oil becomes oxidized (that is, acted on by oxygen in the air), the oil changes from white to black, and the result is a blackhead. This is how the two types of comedones develop.
MEso 81 has a complete formulation for comedo & oily skin, consists of active ingredients such as Zinc PCA, Sodium PCA, Zinc Glycerine , Silk Silika, Burdock Extract & Tea Tree Oil. Zinc PCA is effective for suppression of over active sebum secretion that cause blackhead & clogged pores development.Besides that , it also delays aging process by reducing free radicals formation that leads to wrinkles. Sodium PCA , derived from Amino Acid is non-comedogenic & non-allerginic . Similar to Zink Glycerine, it is high moisture binding raw material that keeps skin hydrated. A nano-tech derivative Silk Silica aids delivery of protein to strengthen skin texture thus increase firmness of the skin.Burdock extract is a powerful anti toxin ingredient to heal skin infected with acne & comedo whereas tea tree oil is effective in anti microbial activity especially acne prone skin.